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Nephrology

<ѻý class="page-description">News, opinions and meeting coverage in nephrology.
FDA Panel Rejects SGLT1/2 Inhibitor for Type 1 Diabetes

— Data too uncertain to support sotagliflozin in subset with chronic kidney disease, advisors say

FDA ADCOMM sotagliflozin over a computer rendering of chronic kidney disease.

Latest in Nephrology

Tricuspid Valve Replacement Finds Surer Footing With TRISCEND II's 1-Year Report

Evoque device helped outcomes in severe tricuspid regurgitation, with some safety caveats

Oct 31, 2024
Ex-Gov. May Face Charges Over COVID; Autism Dx Up 175%; Can Fasting Help Kidneys?

Health news and commentary gathered by ѻý staff

Oct 31, 2024
FDA Staff Not Quite Sold on Sotagliflozin for T1D Patients With CKD

SGLT1/SGLT2 inhibitor has another shot in T1D, but now in more narrow patient population

Oct 30, 2024
ASA Advises No Longer Holding GLP-1 Agents Prior to Surgery for Most Patients

New guidance replaces earlier rec of a 1-week and 1-day hold of injectable and oral GLP-1 agents

Oct 30, 2024
FDA Staff Not Quite Sold on Sotagliflozin for T1D Patients With CKD

SGLT1/SGLT2 inhibitor has another shot in T1D, but now in more narrow patient population

ASA Advises No Longer Holding GLP-1 Agents Prior to Surgery for Most Patients

New guidance replaces earlier rec of a 1-week and 1-day hold of injectable and oral GLP-1 agents

Nephrology Case Studies

Persistent Shoulder Pain in a Dialysis Patient?

Consider metastatic or ectopic calcification in diagnosing unexplained symptoms in ESRD patients

A mature male describes his shoulder pain to his male doctor.
What Caused This Man's Weakness and Hematuria?

Lab tests, physical exam not helpful -- but history-taking offers a clue

image

More in Nephrology

Colorado Teen Fights Kidney Failure After Eating McDonald's Quarter Pounders

Deadly E. coli outbreak has been tentatively traced to contaminated onions

Oct 30, 2024
A selfie of Brittany Randall and her daughter Kamberlyn Bowler in Grand Junction Colorado in the summer of 2024.
Wegovy Cut Albuminuria by Half in Non-Diabetic CKD

However, 24 weeks of the GLP-1 had no impact on eGFR

Oct 29, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
Early AKI Care Recommendations Did Not Improve Patient Outcomes

Personalized recs were made by team of physicians and pharmacists within an hour of diagnosis

Oct 29, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
SGLT2 Inhibitor Carry-Over Benefits Last How Long?

Trial follow-up defines the need for long-term treatment in protecting the kidneys and heart

Oct 29, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
Kidney Disease Genetic Risk Common in West Africans

Observational study points to genetic risk allele dose-response

Oct 29, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
No Kidney Benefit With Finerenone in Heart Failure Patients

Anti-mineralocorticoid agent reduced albuminuria, but not eGFR-based kidney outcome

Oct 28, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
Complement Inhibitor Shows Promise for Rare Kidney Disorder

Ravulizumab reduced proteinuria, stabilized eGFR in IgA nephropathy

Oct 28, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
Interim ALIGN Data: Atrasentan Cuts Proteinuria in IgA Nephropathy

Surrogate endpoint of urinary protein-to-creatinine ratio "widely considered to be predictive"

Oct 27, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
Alternative Pathway Inhibition Makes Good in IgA Nephropathy

Treatment with iptacopan reduces proteinuria in interim APPLAUSE-IgAN analysis

Oct 26, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
Pediatric Febrile UTI May Hurt Kidney Function

Study also raises question of antibiotic prophylaxis in kids with common congenital anomaly

Oct 26, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
Metformin and Congenital Abnormalities; Deprescribing in Patients With Dementia

Also in TTHealthWatch: best medications for opioid use disorder

Oct 26, 2024
TTUHSC EL PASO HEALTHWATCH with their logo and photos of Rick Lange, MD, and Elizabeth Tracey
Kidney Transplant Trouble Spelled Out for Newer Rejection Episode Categories

Study details an intermediate prognosis with newer microvascular inflammation phenotypes

Oct 25, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
Ozempic Linked With Lower Risk of Alzheimer's Diagnosis

Large observational study suggests further research is warranted

Oct 24, 2024
 A computer rendering of amyloid plaques forming on nerve cells.
Scripts for GLP-1, SGLT2 Drugs on the Rise in Type 1 Diabetes Patients

Findings leave researcher "concerned"

Oct 23, 2024
 A photo of a woman holding out a semaglutide injection pen.
More in Nephrology

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